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Collaborators

Michael Ailion and the Ailion lab:

Μichael Ailion is an Associate Professor at the Department of Biochemistry at the University of Washington. I joined Michael's lab in 2012 and since then we have been working together in two separate projects: (1) understanding the mechanism of dense-core vesicle biogenesis and (2) how Gq signaling regulates locomotion in C. elegans. In 2019 we received a NIH grant to study DCV biogenesis pathways and in 2020 we received a NIH grant to investigate pathways involved in the regulation of the NALCN/NCA channel in C. elegans.  

Jihong Bai and the Bai lab:

Jihong Bai is an Associate Professor at the Basic Sciences Division at the Fred Hutch and a long lasting collaborator. Currently we collaborate on two projects where we investigate the role of the GPCR kinase GRK-2 in C. elegans locomotion and swimming. In 2020 we received a NIH grant with the goal to investigate pathways involved in the regulation of the NALCN/NCA channel in C. elegans.  

Dana Miller and the Miller lab: 

Dana Miller is an Associate Professor of Biochemistry at the University of Washington. Together we investigate how the transcription factor HIF-1 mediates survival in hydrogen sulfide. Caenorhabditis elegans HIF-1 Is Broadly Required for Survival in Hydrogen Sulfide

Suzanne Hoppins and the Hoppins lab: 

Suzanne Hoppins is an Associate Professor of Biochemistry at the University of Washington. The Hoppins lab and I built a worm model to study mutations in mitofusin genes that cause disease in humans. 

David Raizen and the Raizen lab: 

David Raizen is an Associate Professor of Neurology at the University of Pennsylvania. The Raizen lab and I investigate how sensory neurons through GRK-2 regulate locomotion quiescence in C. elegans.  

David Fay and the Fay lab: 

David Fay is a Professor at the Department of Molecular Biology at the University of Wyoming. The goal of our collaboration is to identify proteins that interact with SYM-3/4 two highly conserved proteins, which play a role in the function of the epidermal aECM during C. elegans embryogenesis.

Mentees

Michael Crawford: 

Michael Crawford graduated from the UW as a Biochemistry major and on January 2020 he joined Michael Ailion's lab as a research scientist I. Michael is my right hand and the best collaborator anyone could wish for. He is involved is several projects with great interest in cell biology and imaging. 

Christo Mitchell: 

Christo is a UW undergraduate student and Biochemistry major. Christo investigates how the sensory system affects locomotion behavior in C. elegans. 

Olivia Podhaisky: 

Olivia is a UW undergraduate student and Biochemistry major. Olivia investigates how the sensory system affects locomotion behavior in C. elegans.  

Old mentees

Jerome Cattin Ortolá: â€‹

Jerome was a UW Biochemistry graduate student at the Ailion lab and my close collaborator for several years. Currently he is a postdoctoral researcher at Sean Munro's lab at the LMB in Cambridge, England. Jerome and I worked closely in questions related to dense core vesicle biogenesis. Together we published the following manuscripts: 

EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells, 

The dense-core vesicle maturation protein CCCP-1 binds RAB-2 and membranes through its C-terminal domain

The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles

 

 

Jill Hoyt: 

Jill was a UW Biochemistry graduate student at the Ailion lab and my mentee for four years. Together we published the manuscript: 

The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling in Caenorhabditis elegans

Brantley Coleman: 

Brantley was a UW Biochemistry graduate student at the Ailion lab and my mentee for four years. Together we published the manuscript: 

Modulation of Gq-Rho Signaling by the ERK MAPK Pathway Controls Locomotion in Caenorhabditis elegans

Vanessa Wilson:

Vanessa was a UW Biochemistry undergraduate student. She is currently a clinical researcher at Cedars-Sinai. 

Michael Dreyfuss: 

Michael was an undergraduate student at the Chalfie lab at Columbia University. He completed his MD/PhD at Weill Cornell Medicine. 

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